Jan 29, 2013 · Well, horizontal gene transfer is a pretty new concept that we don't fully understand yet. One thing is for sure: it's very different from vertical gene transfer, in which an a parental organism transfers genetic information to its offspring. Without going in to too much detail, we can say that horizontal gene transfer is a process that occurs over time in which an organism transfers genetic information to an organism other than its offspring. The Basic Difference Between Horizontal and Vertical Gene Transfer. Gene transfer refers to the transfer of DNA containing functional genes between any two organisms. This exchange occurs naturally as well as artificially, and is of two types - horizontal and vertical. These types are discussed and differentiated in the following BiologyWise article.
Especially, plasmid DNA gene therapy is used for cardiovascular disease because plasmid DNA transfer is possible for cardiac or skeletal muscle. Clinical angiogenic gene therapy using plasmid DNA gene transfer has been attempted in patients with peripheral artery disease, but a phase III clinical trial did not show sufficient efficiency. N. Rohner, in Encyclopedia of Evolutionary Biology, 2016. Horizontal Gene Transfer. Horizontal gene transfer also known as lateral gene transfer is the process by which an organism incorporates genetic material from another organism without mating. Horizontal gene transfer is traditionally believed to be restricted to bacteria and unicellular eukaryotes; however, recent work challenges this ...
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